孙书宏

发布者:营养与食品卫生学系发布时间:2023-09-07浏览次数:307




孙书宏,理学博士,中共党员

 

教育经历:

2023.08至今,南京医科大学,皇冠9393体育平台,讲师

2017.09-2023.05,美国斯克里普斯研究所(The Scripps Research Institute),博士后

2012.09-2017.07,北京师范大学,博士

2008.09-2012.07,南京师范大学,学士

 

联系方法:

邮箱:sunsh@njmu.edu.cn

 

研究方向:

基于基因多态性与环境多样性研究天然膳食因子与特异性药物对蛋白质折叠错误疾病的修复作用机制

 

研究论文与专利:

1.     Sun S*, Wang C*, Zhao P; Kline GM, Grandjean JMD, Jiang X, Labaudiniere R, Wiseman RL, Kelly JW, Balch WE. Capturing the Conversion of the Pathogenic Alpha-1-Antitrypsin Fold by ATF6 Enhanced Proteostasis. Cell Chem. Biol. 2023 Jan 19;30(1):22-42.e5.

2.     Sun S*, Wang R, Song J, Guan M, Li N, Zhang X, Zhao Z, Zhang J. Blocking gp130 Signaling Suppresses Autotaxin Expression in Adipocytes and Improves Insulin Sensitivity in Diet-induced Obesity. J Lipid Res. 2017 Nov;58(11):2102-2113. (封面故事)

3.     Sun S*, Zhang X*, Lyu L, Li X, Yao S, Zhang J. Autotaxin Expression Is Regulated at the Post-transcriptional Level by the RNA-binding Proteins HuR and AUF1. J Biol Chem. 2016 Dec 9;291(50):25823-25836.

4.     Wang C*, Zhao P*, Sun S*, Teckman J, Balch WE. Leveraging Population Genomics for Individualized Correction of the Hallmarks of Alpha-1 Antitrypsin Deficiency. Chronic Obstr Pulm Dis. 2020 Jul;7(3):224-246.

5.     Wang C*, Scoot SM*, Sun S, Zhao P, Hutt DM, Shao H, Gestwicki JE, Balch WE. Individualized management of genetic diversity in Niemann-Pick C1 through modulation of the Hsp70 chaperone system. Hum Mol Genet. 2020 Jan 1;29(1):1-19.

6.     Chen W, Jiang G, Sun S, Lu Y, Ma F, Li B. Identification of differentially expressed genes in American cockroach ovaries and testes by suppression subtractive hybridization and the prediction of its miRNAs. Mol Genet Genomics. 2013 Nov;288(11):627-38.

7.     Loguercio S, Calverley B, Wang C, Shak D, Zhao P, Sun S, Budinger S, Balch WE. Understanding the host-pathogen evolutionary balance through Gaussian process modeling of SARS-CoV-2. Patterns. 2023 Jul 21;4(8):100800

8.     张俊杰;孙书宏;宋建稳. Gp130抑制剂在制备干预与治疗肥胖导致的血糖代谢疾病产品中的应用. 专利号:ZL201710320342.5


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